Human Leukocyte antigen B27 (HLA- B27) belongs to a group of cell surface glycoproteins which are expressed on most nucleated human cells and platelets. It is a major histocompatibility complex (MHC) class I molecule. The presence of HLA – B27 is strongly associated with ankylosing spondylitis and some inflammatory disorders like Reiters syndrome, inflammatory bowel syndrome, etc. The binding ability of specific monoclonal antibodies to the antigenic determinants expressed by leucocytes on the surface forms the basis of this test. HLA-B 27 test is generally advised in patients suffering from joint pain where the diagnosis of ankylosing spondylitis is suspected. A positive test result indicates higher chances of developing this disease. Avail of the service by booking the HLA-B27 test online at an affordable rate, at your doorstep.
