Cytomegalovirus infection usually goes unnoticed in healthy people, but it can be fatal in immunocompromised people such as HIV-infected people, organ transplant recipients, or newborn babies. Seronegative female patients infected during pregnancy can transmit the disease to the developing fetus, resulting in congenital abnormalities. The Cytomegalovirus-IgG test is important for assessing the patients immunity status and detecting seroconversion. A significant increase in the anti-cytomegalovirus IgG titer is indicative of a recent or past infection or reactivation of a latent infection.
