Thyroglobulin is a key protein in the thyroid gland that is essential for the synthesis of thyroxine (T4) and triiodothyronine (T3). Antithyroglobulin antibody test measures levels of antibodies to thyroglobulin. This test helps to identify autoimmune diseases involving the thyroid gland. The presence of thyroid autoantibodies causes disorders such as Hashimotos thyroiditis, Graves disease, Hypothyroidism, Thyroid cancer, etc. Women with high levels of ATG might miscarry or be infertile. While in cases of neonatal hypothyroidism, the detection of ATG in the infant suggests transplacental antibody transfer, particularly if the mother has a history of autoimmune thyroiditis or detectable thyroid autoantibodies.
